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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
steatotic liver disease
Summary
- Synonym
-
- Fatty change of liver
- SLD
- Steatosis of liver
- alcoholic fatty liver
- fatty liver disease
- hepatic lipidosis
- hepatic steatosis
- Definition
- A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes.
- Super Class
- lipid storage disease liver disease
External Links
- Disease Ontology
- DOID:9452
- Mondo Disease Ontology
- MeSH
- UMLS
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 2182 | ACSL4 | acyl-CoA synthetase long chain family member 4 | |
| 2194 | FASN | fatty acid synthase | |
| 2203 | FBP1 | fructose-bisphosphatase 1 | |
| 2215 | FCGR3B | Fc gamma receptor IIIb | |
| 2222 | FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | |
| 2350 | FOLR2 | folate receptor beta | |
| 2526 | FUT4 | fucosyltransferase 4 | |
| 2531 | KDSR | 3-ketodihydrosphingosine reductase | |
| 2538 | G6PC1 | glucose-6-phosphatase catalytic subunit 1 | |
| 2539 | G6PD | glucose-6-phosphate dehydrogenase |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 14377 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 15558 | Htr2a | 5-hydroxytryptamine (serotonin) receptor 2A | |
| 16333 | Ins1 | insulin I | |
| 16334 | Ins2 | insulin II | |
| 16846 | Lep | leptin | |
| 19013 | Ppara | peroxisome proliferator activated receptor alpha | |
| 19017 | Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | |
| 22228 | Ucp2 | uncoupling protein 2 (mitochondrial, proton carrier) | |
| 67800 | Dgat2 | diacylglycerol O-acyltransferase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24385 | Gck | glucokinase | |
| 24505 | Ins1 | insulin 1 | |
| 24506 | Ins2 | insulin 2 | |
| 25608 | Lep | leptin | |
| 25634 | G6pc1 | glucose-6-phosphatase catalytic subunit 1 | |
| 25747 | Ppara | peroxisome proliferator activated receptor alpha | |
| 29595 | Htr2a | 5-hydroxytryptamine receptor 2A | |
| 54315 | Ucp2 | uncoupling protein 2 | |
| 83516 | Ppargc1a | PPARG coactivator 1 alpha | |
| 252900 | Dgat2 | diacylglycerol O-acyltransferase 2 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 378695 | ins.L | insulin L homeolog | Xenopus laevis (African clawed frog) | |
| 378696 | ins.S | insulin S homeolog | Xenopus laevis (African clawed frog) | |
| 395003 | dgat2 | diacylglycerol O-acyltransferase 2 | Xenopus tropicalis (tropical clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P00709 | Alpha-lactalbumin | |
| P04040 | Catalase | |
| P04180 | Phosphatidylcholine-sterol acyltransferase | |
| P04798 | Cytochrome P450 1A1 | |
| P05062 | Fructose-bisphosphate aldolase B | |
| P05091 | Aldehyde dehydrogenase, mitochondrial | |
| P05093 | Steroid 17-alpha-hydroxylase/17,20 lyase | |
| P05177 | Cytochrome P450 1A2 | |
| P05187 | Alkaline phosphatase, placental type | |
| P05362 | Intercellular adhesion molecule 1 |
