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Standards Ontologies Notations
obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
External Links
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 151 - 160 of 333 in total
Gene ID Gene Symbol Description Source
5106 PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
5168 ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
5209 PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
5214 PFKP phosphofructokinase, platelet
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
5310 PKD1 polycystin 1, transient receptor potential channel interacting
Displaying entries 11 - 20 of 36 in total
Gene ID Gene Symbol Description Source
15275 Hk1 hexokinase 1
15277 Hk2 hexokinase 2
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
16332 Inppl1 inositol polyphosphate phosphatase-like 1
16846 Lep leptin
16847 Lepr leptin receptor
17869 Myc myelocytomatosis oncogene
18166 Npy1r neuropeptide Y receptor Y1
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
18609 Pdx1 pancreatic and duodenal homeobox 1
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24267 Comt catechol-O-methyltransferase
24377 G6pd glucose-6-phosphate dehydrogenase
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24385 Gck glucokinase
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24835 Tnf tumor necrosis factor
25058 Hk1 hexokinase 1
25059 Hk2 hexokinase 2
25233 Akt2 AKT serine/threonine kinase 2
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32974 Zw Zwischenferment
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37028 ACOX1 acyl-CoA oxidase 1
37447 Sdc Syndecan
39404 INPP5E Inositol polyphosphate 5-phosphatase E
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
44643 Cnx99A Calnexin 99A
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024