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Standards Ontologies Notations
obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
External Links
Disease Ontology
DOID:9970
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 281 - 290 of 333 in total
Gene ID Gene Symbol Description Source
55902 ACSS2 acyl-CoA synthetase short chain family member 2
55907 CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
55959 SULF2 sulfatase 2
56261 GPCPD1 glycerophosphocholine phosphodiesterase 1
56623 INPP5E inositol polyphosphate-5-phosphatase E
56624 ASAH2 N-acylsphingosine amidohydrolase 2
56848 SPHK2 sphingosine kinase 2
56963 RGMA repulsive guidance molecule BMP co-receptor a
56994 CHPT1 choline phosphotransferase 1
57103 TIGAR TP53 induced glycolysis regulatory phosphatase
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
11652 Akt2 thymoma viral proto-oncogene 2
11668 Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1
11815 Apod apolipoprotein D
12015 Bad BCL2-associated agonist of cell death
12846 Comt catechol-O-methyltransferase
12894 Cpt1a carnitine palmitoyltransferase 1a, liver
14380 G6pd2 glucose-6-phosphate dehydrogenase 2
14381 G6pdx glucose-6-phosphate dehydrogenase X-linked
14433 Gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying entries 11 - 20 of 27 in total
Gene ID Gene Symbol Description Source
25239 Apod apolipoprotein D
25513 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
25608 Lep leptin
25703 Rbp4 retinol binding protein 4
25747 Ppara peroxisome proliferator activated receptor alpha
25757 Cpt1a carnitine palmitoyltransferase 1A
29260 Tlr4 toll-like receptor 4
29535 Pdx1 pancreatic and duodenal homeobox 1
29595 Htr2a 5-hydroxytryptamine receptor 2A
54315 Ucp2 uncoupling protein 2
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
32974 Zw Zwischenferment
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37028 ACOX1 acyl-CoA oxidase 1
37447 Sdc Syndecan
39404 INPP5E Inositol polyphosphate 5-phosphatase E
43191 Hex-t2 Hexokinase testis 2
43222 Tl Toll
44643 Cnx99A Calnexin 99A
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024