GlyCosmos Portal

GlyCosmos Diseases

List of diseases involving glycan related genes. The information of each database of Glyco-Disease Genes Database (GDGDB), DisGeNET, and Alliance of Genome Resources is integrated into one list.

Database	Last Updated
Alliance of Genome Resources	February 28, 2024
DisGeNET	February 14, 2024
Glyco-Disease Genes Database (GDGDB)	January 25, 2017

Disease ID	Disease Name	Gene Symbol	Gene ID ▼
DOID:14250	Down syndrome	ADE3 INP51 INP52 INP53 MIS1 MTHFD1 Mthfd1 Mthfd1 O-fut2 POFUT2 Pofut2 Pofut2 RpLP0 SYNJ1 SYNJ2 Synj1 Synj2 Synj2 TUB1 TUB3 TUBA1A Tuba1a Tuba1a mec-12 pad-2 pofut2 pofut2 pug unc-26 ﾎｱTub84B ﾎｱTub84D	108156 175419 178284 20975 22142 23275 259529 309686 31098 40451 40848 40904 41279 4522 64158 64300 777668 779585 7846 80294 84018 852378 85238 853118 854276 854815 854889 854915 855618 8867 8871
DOID:674	cleft palate	ADE3 CDC42 CDC42 COLEC11 Cdc42 Cdc42 Cdc42 MIS1 MTHFD1 Mthfd1 Mthfd1 SDC2 Sdc pug	108156 12540 32981 37447 41279 4522 6383 64300 64465 78989 850930 852378 853118 998
DOID:7693	abdominal aortic aneurysm	ACE ADE3 AHCY Ahcy Ahcy Ahcy Ahcyl MIS1 MTHFD1 Mthfd1 Mthfd1 PLA2G7 PON1 Pla2g7 Pon1 Pon1 SAH1 SELL ahcy-1 ahcy.L ahcy.S paf-2 pug	108156 11615 1636 172408 180704 18979 191 269378 27226 29443 32471 41279 4522 503669 503682 5444 6402 64300 7941 84024 852378 853118 856766
DOID:0080240	non-syndromic X-linked intellectual disability 106	OGT Ogt Ogt ogt-1 ogt.1 ogt.2 ogt.L ogt sxc	108155 176000 26295 337685 35486 447694 553157 652952 8473
DOID:1712	aortic valve stenosis	ACAN ENO1 ENO2 ENO3 LGALS3 OGT Ogt Ogt PLPP3 ogt-1 ogt.1 ogt.2 ogt.L ogt sxc	108155 176 176000 2027 26295 337685 35486 3958 447694 553157 652952 8473 853169 856579 8613
DOID:6000	congestive heart failure	ACAN ACE ALOX12 ALOX15 AMD1 AMPD1 Alox12 Ampd1 Ampd1 CAT CHI3L1 CS CTS2 CYP11B1 CYP1A2 FADS1 FADS2 FOL2 GCH1 Gch1 Gch1 Idgf1 Idgf2 Idgf3 Idgf4 LGALS3 MDH1 MDH2 MDH2 MFN1 MGM1 NCAM1 OGT OPA1 Ogt Ogt Opa1 Opa1 PARP1 PDE2 PDE9A PLA2G7 PLC1 PLCD1 PLD2 Parp1 Parp1 Pde9 Pde9a Pde9a Pla2g7 Plcd1 Plcd1 Pld2 Pld2 Pu RAC1 Rac1 Rac1 SELP SLC2A4 SPO14 STS cat-4 cht-1 ogt-1 ogt.1 ogt opa1 paf-2 parp-1 parp1 sxc	108155 1116 11684 142 1431 14528 1544 1584 1636 171116 176 176000 179472 180628 180704 18585 18799 18806 191569 19353 229665 239 246 24655 25028 25097 25591 26295 2643 266823 270 27226 29244 31926 32233 3355109 337685 34978 34979 34981 35486 363875 37415 3958 3992 412 4191 4684 492332 4976 5152 5333 5338 553157 55669 560788 5879 6403 6517 74143 7941 847 8473 851977 853183 853777 853902 853994 854386 854542 854973 855860 9415
DOID:653	purine-pyrimidine metabolic disorder	ADE16 ADE17 ATIC Atic Atic DAL1 DPYS Dpys Dpys PNP1 PNP Pnp Pnp R12E2.11 UMPS Umps dhp-1 dhp-2 r-l umps-1	108147 172008 172464 176453 177852 1807 18950 22247 290029 42493 471 4860 64705 65135 7372 81643 850715 850906 854845 855149
DOID:0050387	nonpapillary renal cell carcinoma	FHIT HDAC1 MTHFD2 PON1 SDHA	10797 2272 3065 5444 6389
DOID:4451	renal carcinoma	FHIT HDAC1 MTHFD2 PON1 SDHA	10797 2272 3065 5444 6389
DOID:4473	sarcomatoid renal cell carcinoma	FHIT HDAC1 MTHFD2 PON1 SDHA	10797 2272 3065 5444 6389