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ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Summary

Gene Symbol

St6gal1

Organism

Cavia porcellus (domestic guinea pig)

External Links

NCBI Gene: 100730025
KEGG Gene ID: cpoc:100730025
PubChem: 100730025

Annotation

Keyword

Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
H0UVP1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation via asparagine	IEA	30032202
sialylation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

sialylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation [inference]

protein N-linked glycosylation via asparagine

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi apparatus	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying 1 entry
GO Term	Evidence Code	PMID
beta-galactoside alpha-2,6-sialyltransferase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

sialyltransferase activity [inference]

beta-galactoside alpha-2,6-sialyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00778

Name

beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.3.1]

References

2408023

Reactions

Displaying 1 entry
KEGG Reaction	Enzyme	Acceptor	Product
R05990	2.4.3.1	G78059CC	G56749GV

Rhea

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1)-ceramide + CMP

Enzyme

2.4.3.1

PMID

2460092

N-acetyl-β-lactosamine + CMP-N-acetyl-β-neuraminate

H⁺ + N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosamine + CMP

Enzyme

2.4.3.1

PMID

a β-D-galactoside + CMP-N-acetyl-β-neuraminate

an N-acetyl-α-neuraminyl-(2→6)-β-D-galactosyl derivative + H⁺ + CMP

Enzyme

2.4.3.1

PMID

Ortholog

Displaying entries **31 - 40** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Loxodonta africana	100664378		LOXAF11093
Equus caballus	100059539		HORSE14122
Sus scrofa	100302026		PIGXX05342
Bos taurus	282073		BOVIN14810
Capra hircus	100861310		CAPHI12124
Ovis aries	100913159		SHEEP01534
Oryctolagus cuniculus	100353188		RABIT04668
Dipodomys ordii	105999709		DIPOR21904
Cricetulus griseus	100689389		CRIGR17713
Mus musculus	20440		MOUSE19129

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: August 19, 2024