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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase domain 8
Summary
- Gene Symbol
-
- ADAM8
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell-cell adhesion | ||
| positive regulation of cellular extravasation | ||
| cell morphogenesis | ||
| proteolysis | ||
| positive regulation of protein secretion |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ficolin-1-rich granule membrane | ||
| tertiary granule | ||
| plasma membrane | ||
| tertiary granule membrane | ||
| cell surface |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| zinc ion binding | ||
| tumor necrosis factor receptor superfamily binding | ||
| immunoglobulin receptor binding | ||
| metalloendopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Disintegrin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain superfamily |
| Disintegrin domain |
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Disease
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 11501 | MGI:107825 | MOUSE57441 | ||
| 181489 | WB:WBGene00000074 | |||
| 368917 | ZFIN:ZDB-GENE-030616-622 | DANRE06089 | ||
| 499285 | RGD:1566394 | RATNO16893 | ||
| 747844 | 9598_0:002bd9 | PANTR01845 | ||
| 3772109 | FB:FBgn0265140 | |||
| 100005593 | ZFIN:ZDB-GENE-070808-1 | |||
| 100156146 | PIGXX08737 | |||
| 100342070 | RABIT07105 | |||
| 100390068 | CALJA06434 |
