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MIRAGE
a disintegrin and metallopeptidase domain 22
Summary
- Gene Symbol
-
- Adam22
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Integrin
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| myelination in peripheral nervous system | ||
| gliogenesis | ||
| neurotransmitter receptor localization to postsynaptic specialization membrane | ||
| neurotransmitter receptor localization to postsynaptic specialization membrane | ||
| positive regulation of protein localization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| membrane | ||
| axon | ||
| axon initial segment | ||
| axon initial segment |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metalloendopeptidase activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Disintegrin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain superfamily |
| Disintegrin domain |
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 4185 | FB:FBgn0259110 | ||
| 8745 | FB:FBgn0259110 | ||
| 11488 | FB:FBgn0259110 | ||
| 11495 | WB:WBGene00006804 | ||
| 11496 | Xenbase:XB-GENE-957019 | ||
| 23792 | FB:FBgn0259110 | ||
| 23793 | WB:WBGene00006804 | ||
| 53616 | Xenbase:XB-GENE-957019 | HUMAN89718 | |
| 56777 | FB:FBgn0259110 | ||
| 56806 | FB:FBgn0259110 |
