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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione reductase
Summary
- Gene Symbol
-
- Gsr
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative initiation
- Cytoplasm
- Disulfide bond
- FAD
- Mitochondrion
- NADP
- Oxidoreductase
- Redox-active center
- Reference proteome
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| P47791 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell redox homeostasis | ||
| cellular response to oxidative stress | ||
| spermatogenesis | ||
| cellular oxidant detoxification | ||
| glutathione metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| NADP binding | ||
| identical protein binding | ||
| glutathione binding | ||
| glutathione-disulfide reductase (NADP) activity | ||
| flavin adenine dinucleotide binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- glutathione reductase
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11724 | limb-girdle muscular dystrophy | |
| DOID:11758 | iron deficiency anemia | |
| DOID:12241 | beta thalassemia | |
| DOID:12556 | acute kidney tubular necrosis | |
| DOID:12858 | Huntington's disease | |
| DOID:1307 | dementia | |
| DOID:13328 | diabetic cataract | |
| DOID:224 | transient cerebral ischemia | |
| DOID:251 | alcohol-induced mental disorder | |
| DOID:3021 | acute kidney failure |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2936 | HGNC:4623 | HUMAN93295 | ||
| 116686 | 10116_1:0049f8 | RGD:621747 | RATNO11514 | |
| 175467 | WB:WBGene00008117 | |||
| 396625 | PIGXX09217 | |||
| 464099 | PANTR42303 | |||
| 475596 | CANLF04719 | |||
| 506406 | BOVIN22057 | |||
| 553575 | ZFIN:ZDB-GENE-050522-116 | DANRE06966 | ||
| 856014 | SGD:S000006012 | |||
| 100019810 | MONDO25934 |
