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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione reductase
Summary
- Gene Symbol
-
- Gsr
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Alternative initiation
- Cytoplasm
- Disulfide bond
- FAD
- Mitochondrion
- NADP
- Oxidoreductase
- Redox-active center
- Reference proteome
- Transit peptide
- Proteins
| UniProt | Protein Name |
|---|---|
| P47791 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell redox homeostasis | ||
| cellular response to oxidative stress | ||
| spermatogenesis | ||
| cellular oxidant detoxification | ||
| glutathione metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| NADP binding | ||
| identical protein binding | ||
| glutathione binding | ||
| glutathione-disulfide reductase (NADP) activity | ||
| flavin adenine dinucleotide binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- glutathione reductase
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050859 | hemorrhagic cystitis | |
| DOID:0080108 | myoglobinuria | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0080855 | Parkinsonism | |
| DOID:0111363 | Heinz body anemia | |
| DOID:1037 | lymphoid leukemia | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:11476 | osteoporosis | |
| DOID:11713 | diabetic angiopathy |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2936 | HGNC:4623 | HUMAN93295 | ||
| 116686 | 10116_1:0049f8 | RGD:621747 | RATNO11514 | |
| 175467 | WB:WBGene00008117 | |||
| 396625 | PIGXX09217 | |||
| 464099 | PANTR42303 | |||
| 475596 | CANLF04719 | |||
| 506406 | BOVIN22057 | |||
| 553575 | ZFIN:ZDB-GENE-050522-116 | DANRE06966 | ||
| 856014 | SGD:S000006012 | |||
| 100019810 | MONDO25934 |
