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ArfGAP with FG repeats 1

Summary

Gene Symbol

Agfg1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

15463

PubChem

15463

Alliance of Genome Resources

MGI:1333754

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
DNA-binding
Developmental protein
Glycoprotein
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Spermatogenesis
Transport
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8K2K6	HIV-1 Rev-binding protein homolog Nucleoporin-like protein RIP
A0A087WSR7
A0A087WNV1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
acrosome assembly	IMP	11711676 14724135
acrosome assembly	IBA
spermatid nucleus differentiation	IMP	16765935
spermatid nucleus differentiation	IBA
intermediate filament organization	IMP	14724135

GO Hierarchy

biological process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

spermatid nucleus differentiation

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization [inference]

intermediate filament organization

vesicle organization [inference]

secretory granule organization [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

organelle assembly [inference]

acrosome assembly

supramolecular fiber organization [inference]

intermediate filament organization

reproductive process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

cellular process involved in reproduction in multicellular organism [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

acrosome assembly

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

acrosome assembly

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GO Term	Evidence Code	PMID
nucleus	IEA
cytoplasm	IBA
cytoplasmic vesicle	IDA	11711676
cytoplasmic vesicle	IBA
cell projection	IDA	16421295

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle

cell body [inference]

neuronal cell body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
DNA binding	IEA
GTPase activator activity	IEA
zinc ion binding	IEA
metal ion binding

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

arf-GAP domain and FG repeat-containing protein 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
acrosome assembly
intermediate filament organization
metal ion binding
spermatid nucleus differentiation

Displaying 1 entry
InterPro
ArfGAP domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070311	oligoasthenoteratozoospermia	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3267	Xenbase:XB-GENE-5750510	HUMAN67299
Drosophila melanogaster	3268	FB:FBgn0020304
Xenopus tropicalis	15463	Xenbase:XB-GENE-5750510
Drosophila melanogaster	231801	FB:FBgn0020304
Danio rerio	327597		DANRE09297
Xenopus tropicalis	363266	Xenbase:XB-GENE-5750510
Pan troglodytes	459990		PANTR29925
Macaca mulatta	708910		MACMU06401
Monodelphis domestica	100014819		MONDO32596
Taeniopygia guttata	100217620		TAEGU30411

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements