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Carboxylic ester hydrolase
Summary
- Gene Symbol
-
- ace-3
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Neurotransmitter degradation
- Proteomics identification
- Reference proteome
- Serine esterase
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9U295 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of backward locomotion | ||
| acetylcholine catabolic process in synaptic cleft | ||
| acetylcholine catabolic process | ||
| choline metabolic process | ||
| multicellular organismal movement |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| synaptic cleft | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| carboxylic ester hydrolase activity | ||
| cholinesterase activity | ||
| identical protein binding | ||
| acetylcholinesterase activity | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- hydrolase
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Carboxylesterase, type B |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:10487 | Hirschsprung's disease | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:1168 | familial hyperlipidemia | |
| DOID:12858 | Huntington's disease | |
| DOID:1307 | dementia | |
| DOID:14330 | Parkinson's disease | |
| DOID:1826 | epilepsy | |
| DOID:1849 | cannabis dependence |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 43 | HGNC:108 | |||
| 590 | HGNC:983 | |||
| 11423 | MGI:87876 | |||
| 12038 | MGI:894278 | |||
| 6104232 | 6279_0:000c41 | |||
| 9946849 | 7209_0:001a94 | |||
| 25348223 | 51031_0:00148e | |||
| 36383311 | 34506_0:00266c |
