GlyCosmos Portal

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Alternative splicing
Apoptosis
Charcot-Marie-Tooth disease
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Disease variant
Isomerase
Membrane
Microtubule
Mitochondrion
Motor protein
Neurodegeneration
Phosphoprotein
Reference proteome
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
O60333

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
apoptotic process	IEA
neuron-neuron synaptic transmission	ISS
neuromuscular synaptic transmission	ISS
vesicle-mediated transport	IBA
mitochondrion transport along microtubule	IMP	16225668

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

apoptotic process involved in development

vesicle-mediated transport

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

establishment of localization in cell [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

establishment of vesicle localization [inference]

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

organelle localization [inference]

mitochondrion localization [inference]

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

establishment of vesicle localization [inference]

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

synaptic vesicle localization [inference]

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport [inference]

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

anterograde synaptic vesicle transport

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

organelle transport along microtubule [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

mitochondrion transport along microtubule

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

retrograde neuronal dense core vesicle transport

synaptic vesicle cytoskeletal transport [inference]

synaptic vesicle transport along microtubule [inference]

anterograde synaptic vesicle transport

dense core granule cytoskeletal transport [inference]

retrograde neuronal dense core vesicle transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
mitochondrion	IDA	16225668
mitochondrion	IEA
kinesin complex	IBA
microtubule	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	12097473 16225668 20852589 25416956 32814053 35271311 36931259
ATP binding	IEA
microtubule binding	IBA
plus-end-directed microtubule motor activity	IDA	16225668
plus-end-directed microtubule motor activity	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

plus-end-directed microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

kinesin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

plus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinesin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding

Displaying **all 5** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0110154	Charcot-Marie-Tooth disease type 2A1	Alliance of Genome Resources
DOID:2152	ovary epithelial cancer	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:769	neuroblastoma	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 74 in total

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Species	Gene ID	Orthologous MAtrix
Oryzias latipes	101174185	ORYLA15636
Tursiops truncatus	101339795	TURTR16149
Octodon degus	101571909	OCTDE18728
Jaculus jaculus	101598578	JACJA09012
Mustela putorius furo	101688508	MUSPF18621
Chrysemys picta bellii	101953027	CHRPI32766
Ictidomys tridecemlineatus	101957269	ICTTR14976
Chinchilla lanigera	102021353	CHILA18990
Capra hircus	102170718	CAPHI06815
Latimeria chalumnae	102365337	LATCH09830

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OrthoDB (Group)

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Acknowledgements