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MYC proto-oncogene, bHLH transcription factor
Summary
- Gene Symbol
-
- Myc
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Alternative initiation
- Cytoplasm
- DNA-binding
- Glycoprotein
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| P09416 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA damage response | ||
| re-entry into mitotic cell cycle | ||
| protein processing | ||
| response to estradiol | ||
| negative regulation of transcription initiation by RNA polymerase II |
GO Hierarchy
- cellular response to xenobiotic stimulus
- cellular response to dimethyl sulfoxide
- pigmentation
- cellular response to xenobiotic stimulus
- cellular response to dimethyl sulfoxide
- cellular response to xenobiotic stimulus
- cellular response to dimethyl sulfoxide
- positive regulation of cell cycle
- positive regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
cellular metabolic process [inference]
cellular response to stimulus [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to oxygen-containing compound [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
response to organic substance [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to oxygen-containing compound [inference]
response to nitrogen compound [inference]
response to oxygen-containing compound [inference]
cellular response to stimulus [inference]
cellular response to chemical stimulus [inference]
cellular response to organic substance [inference]
cellular response to oxygen-containing compound [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of small molecule metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of nucleotide metabolic process [inference]
negative regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of RNA metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of nucleotide metabolic process [inference]
negative regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of RNA metabolic process [inference]
negative regulation of nitrogen compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of nucleotide metabolic process [inference]
negative regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
positive regulation of small molecule metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of nucleotide metabolic process [inference]
negative regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of RNA metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression
positive regulation of macromolecule biosynthetic process [inference]
regulation of RNA biosynthetic process [inference]
negative regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
regulation of phosphate metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of cellular metabolic process [inference]
positive regulation of phosphorus metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nuclear body | ||
| RNA polymerase II transcription repressor complex | ||
| nuclear envelope | ||
| axon |
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| eukaryotic initiation factor eIF2 binding | ||
| E-box binding | ||
| core promoter sequence-specific DNA binding | ||
| double-stranded DNA binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0001816 | angiosarcoma | |
| DOID:0060318 | acute promyelocytic leukemia | |
| DOID:0080322 | polycystic kidney disease | |
| DOID:0110858 | polycystic kidney disease 1 | |
| DOID:10283 | prostate cancer | |
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:11054 | urinary bladder cancer | |
| DOID:11132 | prostatic hypertrophy | |
| DOID:11476 | osteoporosis | |
| DOID:127 | leiomyoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 31310 | FB:FBgn0262656 | ||
| 102357079 | LATCH15937 | ||
| 30686 | ZFIN:ZDB-GENE-990415-162 | DANRE25540 | |
| 393141 | ZFIN:ZDB-GENE-040426-780 | DANRE28567 | |
| 103033997 | ASTMX11957 | ||
| 103038167 | ASTMX16357 | ||
| 100304504 | ICTPU17904 | ||
| 108268289 | ICTPU32005 | ||
| 113573843 | ELEEL13705 | ||
| 106568625 | SALSA34131 |
