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Standards Ontologies Notations
Guidelines
MIRAGE
inositol 1,4,5-trisphosphate receptor, type 1

Summary
Gene Symbol
  • Itpr1
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
25262
PubChem
25262
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Apoptosis
  • Calcium channel
  • Cytoplasm
  • Cytoplasmic vesicle
  • Disulfide bond
  • Endoplasmic reticulum
  • Isopeptide bond
  • Ligand-gated ion channel
  • Metal-binding
  • Palmitate
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Transmembrane helix
  • Ubl conjugation
Proteins
Displaying all 3 entries
UniProt Protein Name
P29994
  • IP3 receptor isoform 1
  • Inositol 1,4,5-trisphosphate receptor
  • Inositol 1,4,5-trisphosphate receptor type 1
  • Type 1 inositol 1,4,5-trisphosphate receptor
Q5BJS8
C7E1V2
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 31 - 35 of 58 in total
GO Term Evidence Code PMID
voluntary musculoskeletal movement
voluntary musculoskeletal movement
release of sequestered calcium ion into cytosol
release of sequestered calcium ion into cytosol
release of sequestered calcium ion into cytosol
GO Hierarchy
Displaying entries 16 - 20 of 42 in total
GO Term Evidence Code PMID
calcineurin complex
postsynaptic density
postsynaptic density
membrane
sarcoplasmic reticulum
GO Hierarchy
Displaying entries 6 - 10 of 31 in total
GO Term Evidence Code PMID
calcium ion binding
protein binding
ATP binding
calcium-release channel activity
calcium-release channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Rodentia
Group Name
Inositol 1,4,5-trisphosphate receptor
Functional Category
  • C: Energy production and conversion
  • E: Amino acid transport and metabolism
  • I: Lipid transport and metabolism
Displaying all 8 entries
Gene Ontology
calcium channel activity
calcium ion transmembrane transport
calcium ion transport
calcium-mediated signaling
inositol 1,4,5 trisphosphate binding
monoatomic ion channel activity
monoatomic ion transport
release of sequestered calcium ion into cytosol
Alliance of Genome Resources
Expression
Displaying all 8 entries
Location References
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:2841 asthma
Ortholog
Displaying entries 1 - 10 of 60 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
3708 Xenbase:XB-GENE-920765 HUMAN68200
3709 FB:FBgn0010051
3710 FB:FBgn0010051
16438 Xenbase:XB-GENE-920765 MOUSE49714
16440 FB:FBgn0010051
25262 Xenbase:XB-GENE-920765
317697 BOVIN17442
397454 PIGXX04492
460134 PANTR30309
476548 CANLF07320
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025