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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
palmitoyl-protein thioesterase 1
Summary
- Gene Symbol
-
- Ppt1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| endocytosis | ||
| macromolecule catabolic process | ||
| pinocytosis | ||
| negative regulation of cell growth | ||
| protein transport |
GO Hierarchy
biological process
metabolic process [inference]
homeostatic process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| synaptic vesicle membrane | ||
| Golgi apparatus | ||
| neuronal cell body | ||
| intracellular membrane-bounded organelle | ||
| membrane raft |
| GO Term | Evidence Code | PMID |
|---|---|---|
| palmitoyl-(protein) hydrolase activity | ||
| long-chain acyl-CoA hydrolase activity | ||
| lysophosphatidic acid binding | ||
| palmitoyl hydrolase activity | ||
| sulfatide binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- palmitoyl-protein thioesterase 1
- Functional Category
-
- E: Amino acid transport and metabolism
- I: Lipid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
| Gene Ontology |
|---|
| hydrolase activity |
| macromolecule depalmitoylation |
| nervous system development |
| palmitoyl hydrolase activity |
| palmitoyl-(protein) hydrolase activity |
| receptor-mediated endocytosis |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Palmitoyl protein thioesterase |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110721 | neuronal ceroid lipofuscinosis 1 | |
| DOID:0110731 | neuronal ceroid lipofuscinosis 3 | |
| DOID:14503 | neuronal ceroid lipofuscinosis |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP012589
- Gene Name
- palmitoyl-protein thioesterase 1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 5538 | HGNC:9325 | HUMAN49061 | ||
| 19063 | 10090_1:001230 | MGI:1298204 | MOUSE41762 | |
| 31805 | FB:FBgn0030057 | |||
| 191744 | WB:WBGene00004092 | |||
| 281421 | BOVIN27228 | |||
| 406648 | ZFIN:ZDB-GENE-040426-2653 | DANRE16023 | ||
| 448650 | Xenbase:XB-GENE-923070 | |||
| 456789 | PANTR20750 | |||
| 475316 | CANLF03912 | |||
| 693377 | MACMU21827 |
