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MIRAGE

Laminin A

Summary

Gene Symbol

LanA

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

38723

PubChem

38723

Alliance of Genome Resources

FB:FBgn0002526

Annotation

Keyword

Basement membrane
Cell adhesion
Cell projection
Coiled coil
Cytoplasmic vesicle
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Reference proteome
Repeat
Signal
Synapse

Proteins

Displaying 1 entry
UniProt	Protein Name
Q00174	Laminin A chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
cell adhesion	IEA
axon guidance	IMP	12040052
axon guidance	IBA
mesoderm development	IEP	11486054
heart development	IMP	10075841

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

encapsulation of foreign target [inference]

melanotic encapsulation of foreign target

immune response [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

metabolic process [inference]

secondary metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

pigment metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

cellular process [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

cell adhesion mediated by integrin

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

extracellular structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

anatomical structure development [inference]

tissue development

mesoderm development

animal organ development [inference]

heart development

growth [inference]

developmental growth [inference]

developmental growth involved in morphogenesis [inference]

dorsal trunk growth, open tracheal system

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

immune response [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

melanization defense response [inference]

melanotic encapsulation of foreign target

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

negative regulation of biological process [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cellular process [inference]

regulation of cell adhesion

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region
basement membrane	IDA	1425586 18331716 27404358 30260959 7760738
basement membrane	IBA
synaptic vesicle
axon

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic periactive zone

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

basement membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA
extracellular matrix structural constituent	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

signaling receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Laminin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
animal organ morphogenesis
regulation of cell adhesion
regulation of cell migration
regulation of embryonic development
signaling receptor binding
tissue development

Displaying **all 2** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
Laminin G domain

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
collagen-containing extracellular matrix	PMID:26896675
basement membrane	PMID:1425586 PMID:18331716 PMID:27404358 PMID:30260959 PMID:7760738
presynaptic periactive zone	PMID:23054837
membrane	FB:FBrf0231198

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	3909	HGNC:6483
Xenopus tropicalis	3911	Xenbase:XB-GENE-1007923
Homo sapiens	16774	HGNC:6483
Xenopus tropicalis	16776	Xenbase:XB-GENE-1007923
Xenopus tropicalis	38723	Xenbase:XB-GENE-1007923
Xenopus tropicalis	140433	Xenbase:XB-GENE-1007923
Xenopus tropicalis	177956	Xenbase:XB-GENE-1007923

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Last updated: April 7, 2025