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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leptin
Summary
- Gene Symbol
-
- LEP
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of appetite | ||
| determination of adult lifespan | ||
| positive regulation of TOR signaling | ||
| negative regulation of cartilage development | ||
| phagocytosis |
GO Hierarchy
- positive regulation of cold-induced thermogenesis
- positive regulation of cold-induced thermogenesis
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
positive regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of system process [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA binding | ||
| hormone activity | ||
| peptide hormone receptor binding | ||
| protein binding | ||
| leptin receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050848 | obstructive sleep apnea | |
| DOID:0060611 | abdominal obesity-metabolic syndrome | |
| DOID:0080208 | metabolic dysfunction-associated steatotic liver disease | |
| DOID:0111334 | congenital leptin deficiency | |
| DOID:10591 | pre-eclampsia | |
| DOID:10603 | glucose intolerance | |
| DOID:10605 | short bowel syndrome | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102366460 | LATCH05119 | ||
| 564348 | ZFIN:ZDB-GENE-041210-183 | ||
| 100150233 | ZFIN:ZDB-GENE-081001-1 | ||
| 734226 | Xenbase:XB-GENE-980662 | ||
| 108711253 | Xenbase:XB-GENE-17342421 | ||
| 113450645 | PSETE24636 | ||
| 100078019 | ORNAN00888 | ||
| 100930199 | SARHA04155 | ||
| 103116410 | ERIEU08504 | ||
| 100407456 | CALJA42753 |
