NEDD4 E3 ubiquitin protein ligase

Summary
Gene Symbol
  • NEDD4
Organism
Homo sapiens (human)
NCBI Gene
4734
PubChem
4734
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cell membrane
  • Cytoplasm
  • Host-virus interaction
  • Isopeptide bond
  • Neurogenesis
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Transferase
  • Ubl conjugation
  • Ubl conjugation pathway
Proteins
Displaying 1 entry
UniProt Protein Name
P46934
  • Cell proliferation-inducing gene 53 protein
  • HECT-type E3 ubiquitin transferase NEDD4
  • Neural precursor cell expressed developmentally down-regulated protein 4
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
E3 ubiquitin-protein ligase
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
protein polyubiquitination
regulation of dendrite morphogenesis
Displaying all 2 entries
InterPro
HECT domain
HECT, E3 ligase catalytic domain

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025