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Guidelines

MIRAGE

sulfatase modifying factor 1

Summary

Gene Symbol

SUMF1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 536435
KEGG Gene ID: bta:536435
PubChem: 536435

Annotation

Keyword

Calcium
Copper
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Metal-binding
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0P5L5	C-alpha-formylglycine-generating enzyme 1 Sulfatase-modifying factor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein oxidation
post-translational protein modification

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

macromolecule modification [inference]

protein modification process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA	30032202
endoplasmic reticulum lumen

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
formylglycine-generating oxidase activity
cupric ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [inference]

formylglycine-generating oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding [inference]

cupric ion binding

sulfur compound binding [inference]

cupric ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sulfatase modifying factor

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
InterPro
C-type lectin fold
Sulfatase-modifying factor enzyme superfamily
Sulfatase-modifying factor enzyme

KEGG BRITE Database

Orthology

K13444

Name

formylglycine-generating enzyme [EC:1.8.3.7]

References

Rhea

O₂ + a thiol

H₂O + H⁺ + hydrogen sulfide + an organic disulfide

Enzyme

1.8.3.7

PMID

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	58911		MOUSE49559
Homo sapiens	285362		HUMAN68188
Rattus norvegicus	362409		RATNO31971
Pan troglodytes	470739		PANTR30305
Canis lupus familiaris	484681		CANLF07321
Danio rerio	553423		DANRE38296
Macaca mulatta	704112		MACMU27918
Monodelphis domestica	100022619		MONDO29752
Equus caballus	100052857		HORSE11055
Ornithorhynchus anatinus	100092877		ORNAN28433

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.3.0

Last updated: August 4, 2025