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sulfatase modifying factor 1

Summary

Gene Symbol

SUMF1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 536435
KEGG Gene ID: bta:536435
PubChem: 536435

Annotation

Keyword

Calcium
Copper
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Metal-binding
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0P5L5	C-alpha-formylglycine-generating enzyme 1 Sulfatase-modifying factor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein oxidation
post-translational protein modification

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

macromolecule modification [inference]

protein modification process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cupric ion binding
formylglycine-generating oxidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [inference]

formylglycine-generating oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding [inference]

cupric ion binding

sulfur compound binding [inference]

cupric ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sulfatase modifying factor

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
InterPro
C-type lectin fold
Sulfatase-modifying factor enzyme superfamily
Sulfatase-modifying factor enzyme

KEGG BRITE Database

Orthology

K13444

Name

formylglycine-generating enzyme [EC:1.8.3.7]

References

Rhea

O₂ + a thiol

H₂O + H⁺ + hydrogen sulfide + an organic disulfide

Enzyme

1.8.3.7

PMID

Ortholog

Displaying entries **31 - 40** of 82 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Capra hircus	102188808	9925_0:003caf		CAPHI14435
Bos mutus	102268812	72004_1:001dba
Bubalus bubalis	102411474	89462_0:0049fc
Myotis lucifugus	102424680			MYOLU16312
Pelodiscus sinensis	102462137			PELSI15470
Camelus ferus	102521577	419612_0:003134
Vicugna pacos	102539771	30538_0:002349
Physeter catodon	102987747	9755_0:00394c
Callorhinchus milii	103185048			CALMI31315
Chlorocebus sabaeus	103227937			CHLSB10530

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024