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sulfatase modifying factor 1

Summary

Gene Symbol

SUMF1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 536435
KEGG Gene ID: bta:536435
PubChem: 536435

Annotation

Keyword

Calcium
Copper
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Metal-binding
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0P5L5	C-alpha-formylglycine-generating enzyme 1 Sulfatase-modifying factor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein oxidation
post-translational protein modification

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

macromolecule modification [inference]

protein modification process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen
endoplasmic reticulum	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cupric ion binding
formylglycine-generating oxidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor [inference]

formylglycine-generating oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding [inference]

cupric ion binding

sulfur compound binding [inference]

cupric ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sulfatase modifying factor

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
InterPro
C-type lectin fold
Sulfatase-modifying factor enzyme superfamily
Sulfatase-modifying factor enzyme

KEGG BRITE Database

Orthology

K13444

Name

formylglycine-generating enzyme [EC:1.8.3.7]

References

Rhea

O₂ + a thiol

H₂O + H⁺ + hydrogen sulfide + an organic disulfide

Enzyme

1.8.3.7

PMID

Ortholog

Displaying entries **41 - 50** of 82 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Carlito syrichta	103263067			CARSF22071
Ursus maritimus	103669599			URSMA17312
Nannospalax galili	103751201			NANGA07498
Rhinopithecus roxellana	104664268			RHIRO15048
Bison bison bison	104991588	43346_0:002219
Esox lucius	105017007			ESOLU50117
Camelus bactrianus	105074762	9837_0:003145
Camelus dromedarius	105093157	9838_0:002f6c
Ailuropoda melanoleuca	105237960			AILME12020
Macaca nemestrina	105477621			MACNE19201

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024