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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Summary
- Gene Symbol
-
- Klk4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Biomineralization
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Z0M1 |
|
| A0A1R3UDT0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| amelogenesis | ||
| extracellular matrix disassembly | ||
| biomineral tissue development | ||
| protein catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule | ||
| extracellular region | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- kallikrein-4
- Functional Category
-
- I: Lipid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Serine proteases, trypsin domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110057 | amelogenesis imperfecta type 2A1 | |
| DOID:10283 | prostate cancer | |
| DOID:1612 | breast cancer | |
| DOID:2394 | ovarian cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 100400277 | CALJA24518 | |||
| 100433879 | PONAB14635 | |||
| 100586166 | NOMLE00896 | |||
| 100717074 | 10141_0:0014f0 | |||
| 100757055 | 10029_0:0039e0 | CRIGR20278 | ||
| 100957714 | OTOGA00569 | |||
| 101006869 | PAPAN22958 | |||
| 101046161 | SAIBB33344 | |||
| 101089560 | FELCA32926 | |||
| 101146175 | GORGO15951 |
