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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)
Summary
- Gene Symbol
-
- Klk4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Biomineralization
- Disulfide bond
- Glycoprotein
- Metal-binding
- Reference proteome
- Secreted
- Serine protease
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9Z0M1 |
|
| A0A1R3UDT0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| amelogenesis | ||
| extracellular matrix disassembly | ||
| biomineral tissue development | ||
| protein catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| secretory granule | ||
| extracellular region | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| serine-type endopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- kallikrein-4
- Functional Category
-
- I: Lipid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
| InterPro |
|---|
| Serine proteases, trypsin domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110057 | amelogenesis imperfecta type 2A1 | |
| DOID:10283 | prostate cancer | |
| DOID:1612 | breast cancer | |
| DOID:2394 | ovarian cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 103235105 | CHLSB16087 | |||
| 103274728 | CARSF12487 | |||
| 103743714 | 1026970_0:002fe4 | NANGA12521 | ||
| 104873913 | 885580_0:0027fb | |||
| 105497137 | MACNE21522 | |||
| 105528937 | MANLE19980 | |||
| 105595457 | CERAT28695 | |||
| 105723536 | AOTNA32248 | |||
| 105809262 | PROCO22119 | |||
| 105994294 | 10020_0:003466 | DIPOR19035 |
