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kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)

Summary

Gene Symbol

Klk4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56640

PubChem

56640

Alliance of Genome Resources

MGI:1861379

Annotation

Keyword

Biomineralization
Disulfide bond
Glycoprotein
Metal-binding
Reference proteome
Secreted
Serine protease
Signal
Zinc
Zymogen

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9Z0M1	Enamel matrix serine proteinase 1 Kallikrein-like protein 1 Serine protease 17
A0A1R3UDT0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
proteolysis	IEA
extracellular matrix disassembly	IMP	22243248
extracellular matrix disassembly	IBA
protein catabolic process	IMP	22243248
biomineral tissue development	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

organonitrogen compound catabolic process [inference]

protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

extracellular matrix disassembly

extracellular structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

extracellular matrix disassembly

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

odontogenesis [inference]

odontogenesis of dentin-containing tooth [inference]

amelogenesis

anatomical structure formation involved in morphogenesis [inference]

amelogenesis

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
secretory granule	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase activity	IBA
serine-type endopeptidase activity	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

kallikrein-4

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
hydrolase activity
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity

Displaying 1 entry
InterPro
Serine proteases, trypsin domain

Ortholog

Displaying entries **1 - 10** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	354	FB:FBgn0052808
Drosophila melanogaster	3816	FB:FBgn0052808
Drosophila melanogaster	3817	FB:FBgn0052808
Drosophila melanogaster	5653	FB:FBgn0052808
Homo sapiens	9622	HGNC:6365	HUMAN45411
Drosophila melanogaster	11012	FB:FBgn0052808
Drosophila melanogaster	11202	FB:FBgn0052808
Drosophila melanogaster	13646	FB:FBgn0052808
Drosophila melanogaster	13647	FB:FBgn0052808
Drosophila melanogaster	13648	FB:FBgn0052808