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protein kinase AMP-activated catalytic subunit alpha 1
Summary
- Gene Symbol
-
- Prkaa1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Autophagy
- Biological rhythms
- Cholesterol biosynthesis
- Chromatin regulator
- Cytoplasm
- Direct protein sequencing
- Fatty acid biosynthesis
- Glycoprotein
- Magnesium
- Metal-binding
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Transcription regulation
- Ubl conjugation
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| P54645 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glucose import | ||
| cellular response to calcium ion | ||
| negative regulation of TOR signaling | ||
| cellular response to oxidative stress | ||
| cholesterol biosynthetic process |
GO Hierarchy
- rhythmic process
- response to activity
- regulation of circadian rhythm
- regulation of vesicle-mediated transport
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of small molecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
positive regulation of cellular process [inference]
regulation of cellular localization [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| kinase binding | ||
| chromatin binding | ||
| [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity | ||
| histone H2BS36 kinase activity | ||
| protein serine/threonine kinase activity |
GO Hierarchy
molecular function
catalytic activity [inference]
binding [inference]
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12858 | Huntington's disease | |
| DOID:13580 | cholestasis | |
| DOID:14330 | Parkinson's disease | |
| DOID:1612 | breast cancer | |
| DOID:219 | colon cancer | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 181727 | WB:WBGene00020142 | ||
| 43904 | FB:FBgn0023169 | ||
| 100184788 | CIOIN15413 | ||
| 102349521 | LATCH02452 | ||
| 100001198 | ZFIN:ZDB-GENE-030325-1 | DANRE37218 | |
| 103022500 | ASTMX11189 | ||
| 108260283 | ICTPU23023 | ||
| 113570222 | ELEEL07470 | ||
| 106562970 | SALSA56255 | ||
| 115159798 | SALTR71569 |
