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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
paraoxonase 1
Summary
- Gene Symbol
-
- Pon1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Calcium
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- HDL
- Hydrolase
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P55159 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lactone catabolic process | ||
| response to fatty acid | ||
| response to fluoride |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| spherical high-density lipoprotein particle | ||
| high-density lipoprotein particle | ||
| extracellular space |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| metal ion binding | ||
| phospholipid binding | ||
| arylesterase activity | ||
| acyl-L-homoserine-lactone lactonohydrolase activity | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- serum paraoxonase/arylesterase 1
- Functional Category
-
- G: Carbohydrate transport and metabolism
- P: Inorganic ion transport and metabolism
- X: Mobilome: prophages, transposons
| Gene Ontology |
|---|
| acyl-L-homoserine-lactone lactonohydrolase activity |
| aryldialkylphosphatase activity |
| arylesterase activity |
| hydrolase activity |
| metal ion binding |
| response to toxic substance |
| InterPro |
|---|
| Arylesterase |
| Paraoxonase1 |
| Six-bladed beta-propeller, TolB-like |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050731 | vitamin B12 deficiency | |
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:0060669 | cerebral cavernous malformation | |
| DOID:0080001 | bone disease | |
| DOID:0080771 | beta-thalassemia major | |
| DOID:10126 | keratoconus | |
| DOID:10283 | prostate cancer | |
| DOID:1040 | chronic lymphocytic leukemia | |
| DOID:10603 | glucose intolerance | |
| DOID:10608 | celiac disease |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP012808
- Gene Name
- paraoxonase 1
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 125345838 | 214514_0:000b80 | |||
| 125402315 | 447135_0:0001cc | |||
| 126489517 | 100897_0:00429d | |||
| 127194532 | 60746_0:001a94 | |||
| 127216468 | 109678_0:000ca7 | |||
| 127677334 | 10129_0:000d28 | |||
| 128099369 | 564181_0:0041e0 | |||
| 129680848 | 48139_1:0021ad | |||
| 130879769 | 269649_0:000178 | |||
| 131905668 | 42410_0:00126a |
