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fucosyltransferase 10

Summary

Gene Symbol

FUT10

Aliases

alpha (1,3) fucosyltransferase

Organism

Homo sapiens (human)

External Links

NCBI Gene

84750

GGDB ID

gg010

HGNC

19234

mRNA

NM_032664

map

8p12

Protein

NP_116053

OMIM

616931

KEGG Gene ID

hsa:84750

PubChem

84750

Alliance of Genome Resources

HGNC:19234

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lysosome
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6P4F1	Fucosyltransferase X Galactoside 3-L-fucosyltransferase 10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
protein folding	NAS	11698403
N-glycan fucosylation	IDA IEA	19088067
wound healing	NAS	11698403
oligosaccharide biosynthetic process	IEA
fucosylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

catabolic process [inference]

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

small molecule catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

glycosylation [inference]

N-glycan fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

L-fucose metabolic process [inference]

L-fucose catabolic process

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

organic substance catabolic process [inference]

carbohydrate catabolic process [inference]

monosaccharide catabolic process [inference]

hexose catabolic process [inference]

fucose catabolic process [inference]

L-fucose catabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

cellular process [inference]

protein folding

cellular developmental process [inference]

cell development [inference]

hemopoiesis

cell motility [inference]

cell migration [inference]

forebrain cell migration [inference]

telencephalon cell migration [inference]

cerebral cortex cell migration [inference]

cerebral cortex radially oriented cell migration

neuroblast migration

cell division [inference]

stem cell division [inference]

somatic stem cell division [inference]

neuronal stem cell division

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

reproductive process [inference]

fertilization

multicellular organismal process [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis

system development [inference]

nervous system development

cellular developmental process [inference]

cell development [inference]

hemopoiesis

maintenance of cell number [inference]

stem cell population maintenance [inference]

neuronal stem cell population maintenance

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi apparatus	IDA TAS	11698403
endoplasmic reticulum membrane	IEA
nucleoplasm	IDA
lysosome	IEA
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
alpha-(1->3)-fucosyltransferase activity	IBA TAS	11698403
fucosyltransferase activity	IDA	19088067

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity

alpha-(1->3)-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Alpha-(1,3)-fucosyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-(1->3)-fucosyltransferase activity
fucosylation
fucosyltransferase activity
transferase activity

Displaying **all 4** entries
InterPro
Alpha-(1, 3)-fucosyltransferase, metazoan
Fucosyltransferase, N-terminal
GT10-like, C-terminal domain superfamily
Glycosyl transferase family 10

GlycoGene Database (GGDB)

GGDB ID

gg010

Gene Symbol

FUT10

Reactions

Displaying **all 4** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G39213VZ	R	G64669AQ	R	19088067
GDP-Fuc	G46055MA	R	G39775LJ	R	23986452
GDP-Fuc	G25520XG	R	G95617FJ	R	23986452
GDP-Fuc	G52934AK	R	G38753OV	R	23986452

Displaying **all 4** entries
Donor	Acceptor	Reducing terminal(Acceptor)	Product	Reducing terminal(Product)	Reference
GDP-Fuc	G39213VZ	R	G64669AQ	R	19088067
GDP-Fuc	G46055MA	R	G39775LJ	R	23986452
GDP-Fuc	G25520XG	R	G95617FJ	R	23986452
GDP-Fuc	G52934AK	R	G38753OV	R	23986452

Orthologous Gene

Displaying **all 3** entries
Species	Protein	mRNA
Drosophila melanogaster	NP_609288	NM_135444
Rattus norvegicus	NP_001012360	NM_001012360
Mus musculus	AAH62113	BC062113

KEGG BRITE Database

Orthology

K09669

Name

alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-]

References

Ortholog

Displaying entries **21 - 30** of 71 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Cavia porcellus	100721726			CAVPO07225
Otolemur garnettii	100942005			OTOGA06539
Pan paniscus	100972133	9597_0:0024b3		PANPA38012
Papio anubis	101017629			PAPAN39293
Saimiri boliviensis boliviensis	101051129			SAIBB29501
Felis catus	101097389			FELCA08970
Gorilla gorilla gorilla	101134242	9595_0:002955		GORGO40036
Tursiops truncatus	101338016			TURTR02823
Octodon degus	101565521			OCTDE14378
Mustela putorius furo	101682306			MUSPF11056

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024