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Atg3p

Summary

Gene Symbol

ATG3

Organism

Saccharomyces cerevisiae S288C

External Links

NCBI Gene

855741

PubChem

855741

Alliance of Genome Resources

SGD:S000005290

Annotation

Keyword

3D-structure
Acetylation
Autophagy
Cytoplasm
Mitochondrion
Protein transport
Reference proteome
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
P40344	Autophagy-related E2-like conjugation enzyme ATG3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	IMP	25680528
autophagosome assembly	IBA
autophagy of mitochondrion	IMP	19793921
autophagy of mitochondrion	IBA
C-terminal protein lipidation	IDA	15277523

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

catabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

macromolecule modification [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

process utilizing autophagic mechanism [inference]

autophagy

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cytoplasm to vacuole transport by the Cvt pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

organelle disassembly [inference]

autophagy of mitochondrion

cellular component disassembly [inference]

organelle disassembly [inference]

autophagy of mitochondrion

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to membrane

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

cytoplasm to vacuole transport by the Cvt pathway

establishment of protein localization to membrane [inference]

protein targeting to membrane

protein localization to membrane [inference]

establishment of protein localization to membrane [inference]

protein targeting to membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
phagophore assembly site	IDA	25645919 25680528
phagophore assembly site	IBA
cytoplasm	IEA
cytoplasm	HDA	14562095
mitochondrion	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

phagophore

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Atg8-family ligase activity	IMP	11100732
ubiquitin-like protein transferase activity	IEA
Atg8-family conjugating enzyme activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity

ubiquitin-like protein conjugating enzyme activity [inference]

Atg8-family conjugating enzyme activity

ubiquitin-like protein ligase activity [inference]

Atg8-family ligase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity

ubiquitin-like protein conjugating enzyme activity [inference]

Atg8-family conjugating enzyme activity

ubiquitin-like protein ligase activity [inference]

Atg8-family ligase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

-Autophagy-related protein 3

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
Atg8-family ligase activity
autophagosome assembly
nucleophagy

Displaying **all 2** entries
InterPro
Autophagy-related protein 3
Ubiquitin-like-conjugating enzyme Atg3/Atg10

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
cytosol	PMID:26928762
phagophore	PMID:25645919 PMID:25680528
cytoplasm	PMID:14562095
phagophore assembly site	PMID:25645919 PMID:25680528

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	64422	Xenbase:XB-GENE-953266
Xenopus tropicalis	171415	Xenbase:XB-GENE-953266
Xenopus tropicalis	336632	Xenbase:XB-GENE-953266
Xenopus tropicalis	855741	Xenbase:XB-GENE-953266