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beta-1,4-galactosyltransferase 2
Summary
- Gene Symbol
-
- B4GALT2
- Aliases
-
- Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
- N-acetyllactosamine synthase
- beta4Gal-T2
- lactose synthase A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Disulfide bond
- Glycoprotein
- Glycosyltransferase
- Golgi apparatus
- Manganese
- Metal-binding
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| O60909 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| carbohydrate metabolic process | ||
| protein glycosylation | ||
| memory | ||
| locomotory behavior | ||
| visual learning |
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| nucleoplasm | ||
| Golgi apparatus | ||
| Golgi apparatus | ||
| Golgi cisterna membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity | ||
| N-acetyllactosamine synthase activity | ||
| lactose synthase activity | ||
| protein binding | ||
| galactosyltransferase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Beta-1,4-galactosyltransferase 4
- Functional Category
-
- G: Carbohydrate transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| galactosyltransferase activity |
| glycosylation |
| metal ion binding |
| transferase activity |
| InterPro |
|---|
| Beta-1,4-galactosyltransferase |
| Galactosyltransferase, C-terminal |
| Galactosyltransferase, N-terminal |
| Nucleotide-diphospho-sugar transferases |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
GlycoGene Database (GGDB)
- GGDB ID
- gg078
- Gene Symbol
-
- B4GALT2
- Reactions
G71817IG
G81756OO
| Donor | Acceptor | Reducing terminal(Acceptor) | Product | Reducing terminal(Product) | Reference |
|---|---|---|---|---|---|
| UDP-Gal |
G49108TO
|
Benzyl-[beta] |
G00055MO
|
Benzyl-[beta] | |
| UDP-Gal |
G49108TO
|
[beta]-S-pNP |
G00055MO
|
[beta]-S-pNP | |
| UDP-Gal |
G87229LF
|
O(CH2)8COOCH2-mNP |
G50361AJ
|
O(CH2)8COOCH2-mNP | |
| UDP-Gal |
G14651SS
|
[alpha]-1-OMe |
G93379VC
|
[alpha]-1-OMe | |
| UDP-Gal |
G76294XX
|
O(CH2)8COOCH2-mNP |
G80524SB
|
O(CH2)8COOCH2-mNP |
G61418DU
G65889KE
G68544GH
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Drosophila melanogaster | NP_610946 | NM_137102 |
| Mus musculus | NP_059073 | NM_017377 |
| Rattus norvegicus | XP_242992 | XM_242992 |
KEGG BRITE Database
G80858MF
G78059CC
G06239NA
G58896AZ
Rhea
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002947
- Gene Name
- UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2683 | FB:FBgn0027538 | ||
| 8702 | FB:FBgn0027538 | ||
| 8703 | FB:FBgn0027538 | ||
| 8704 | Xenbase:XB-GENE-997913 | ||
| 9334 | FB:FBgn0027538 | ||
| 14595 | FB:FBgn0027538 | ||
| 36585 | Xenbase:XB-GENE-997913 | ||
| 53418 | Xenbase:XB-GENE-997913 | MOUSE41268 | |
| 56336 | FB:FBgn0027538 | ||
| 56375 | FB:FBgn0027538 |
