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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
DNA repair protein RAD51 homolog 3
Summary
- UniProt ID
- O43502
- Gene Symbol
-
- RAD51C
- RAD51L2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Cytoplasm
- DNA recombination
- DNA repair
- DNA-binding
- Disease variant
- Fanconi anemia
- Mitochondrion
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of G2/M transition of mitotic cell cycle |
| GO Term |
|---|
| nucleus |
| cytoplasm |
| intracellular membrane-bounded organelle |
| cell junction |
| mitochondrion |
| cytosol |
| nucleoplasm |
| replication fork |
| Rad51B-Rad51C-Rad51D-XRCC2 complex |
| Rad51C-XRCC3 complex |
| GO Term |
|---|
| DNA binding |
| four-way junction DNA binding |
| ATP binding |
| crossover junction DNA endonuclease activity |
| ATP-dependent DNA damage sensor activity |
Sequence
MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLATACIQHLQLIAEKHKGEEHRKALEDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALLVPALGESWGHAATIRLIFHWDRKQRLATLYKSPSQKECTVLFQIKPQGFRDTVVTSACSLQTEGSLSTRKRSRDPEEEL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 60 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function | Homo sapiens |
| Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function | Homo sapiens |
| Defective homologous recombination repair (HRR) due to BRCA1 loss of function | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
| HDR through Homologous Recombination (HRR) | Homo sapiens |
| Homologous DNA Pairing and Strand Exchange | Homo sapiens |
| Impaired BRCA2 binding to PALB2 | Homo sapiens |
| Meiotic recombination | Homo sapiens |
| Presynaptic phase of homologous DNA pairing and strand exchange | Homo sapiens |
| Resolution of D-loop Structures through Holliday Junction Intermediates | Homo sapiens |
