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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine-protein kinase JAK2
Summary
- UniProt ID
- O60674
- Gene Symbol
-
- JAK2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O60674
- PubChem
- O60674
- The Human Metabolome Database
- HMDBP01194
- The O-GlcNAc Database
- O60674
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Chromatin regulator
- Chromosomal rearrangement
- Cytoplasm
- Disease variant
- Innate immunity
- Magnesium
- Membrane
- Metal-binding
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- Repeat
- SH2 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| euchromatin |
| nucleoplasm |
| extrinsic component of plasma membrane |
| focal adhesion |
| extrinsic component of cytoplasmic side of plasma membrane |
| interleukin-12 receptor complex |
| nucleus |
| cytoplasm |
| cytoskeleton |
| plasma membrane |
Sequence
MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cyclin D associated events in G1 | Homo sapiens |
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | Homo sapiens |
| Erythropoietin activates Phospholipase C gamma (PLCG) | Homo sapiens |
| Erythropoietin activates RAS | Homo sapiens |
| Erythropoietin activates STAT5 | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
| Growth hormone receptor signaling | Homo sapiens |
| IFNG signaling activates MAPKs | Homo sapiens |
| IL-6-type cytokine receptor ligand interactions | Homo sapiens |
| Inactivation of CSF3 (G-CSF) signaling | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
