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Low affinity immunoglobulin gamma Fc region receptor III-B
Summary
- UniProt ID
- O75015
- Gene Symbol
-
- FCGR3B
- CD16B
- FCG3
- FCGR3
- IGFR3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Disulfide bond
- GPI-anchor
- IgG-binding protein
- Immunoglobulin domain
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| immune response |
| cell surface receptor signaling pathway |
| antibody-dependent cellular cytotoxicity |
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| secretory granule membrane |
| extracellular exosome |
| external side of plasma membrane |
| GO Term |
|---|
| IgG receptor activity |
| IgG binding |
| GPI anchor binding |
Sequence
MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 56 | N-linked (GlcNAc...) asparagine |
|
||
| 63 | N-linked (GlcNAc...) asparagine |
|
||
| 82 | N-linked (GlcNAc...) asparagine | |||
| 92 | N-linked (GlcNAc...) asparagine |
|
||
| 180 | N-linked (GlcNAc...) asparagine |
|
||
| 187 | N-linked (GlcNAc...) asparagine |
|
||
|
|
|
G60177UT
G82830MN
G62326NX
G90093AU
G26915XM
G17689DH
G22310AV
G72797UR
G63381RX
G72667IM
G84452RH
G96095QD
G25520XG
G91636VS
G93141AZ
G70418MS
G03382KH
G90717TP
G23863VK
G78059CC
G74430RZ
G31916IQ
G64527OM
G23432EQ
G72902CL
G46687AB
G62389NM
G82119TF
G72291OX
G05724UK
G29011JC
G31936TA
G49874UX
G80858MF
G39188ZX
G39213VZ
G06110VR
G55220VL
G60145BJ
G96771UL
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neutrophil degranulation | Homo sapiens |
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9074 | systemic lupus erythematosus | |
| DOID:9088 | parapsoriasis | |
| DOID:9119 | acute myeloid leukemia | |
| DOID:9123 | eczema herpeticum | |
| DOID:9256 | colorectal cancer | |
| DOID:934 | viral infectious disease | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9360 | intrinsic asthma | |
| DOID:9408 | acute myocardial infarction |
