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MIRAGE
T-cell surface glycoprotein CD3 delta chain

Summary
UniProt ID
P04234
Gene Symbol
  • CD3D
  • T3D
Gene ID
915
Organism
Homo sapiens (human)
GlyGen
P04234
PubChem
P04234
Re-Glyco
P04234
Annotation
Keyword
  • 3D-structure
  • Adaptive immunity
  • Alternative splicing
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • SCID
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 6 entries
GO Term
clathrin-coated endocytic vesicle membrane
cytoplasm
plasma membrane
T cell receptor complex
alpha-beta T cell receptor complex
external side of plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
38 N-linked (GlcNAc...) asparagine
74 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 8 entries
Pathway Name Organism
Cargo recognition for clathrin-mediated endocytosis Homo sapiens
Clathrin-mediated endocytosis Homo sapiens
Downstream TCR signaling Homo sapiens
Generation of second messenger molecules Homo sapiens
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
PD-1 signaling Homo sapiens
Phosphorylation of CD3 and TCR zeta chains Homo sapiens
Translocation of ZAP-70 to Immunological synapse Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0111972 immunodeficiency 19
DOID:627 severe combined immunodeficiency
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025