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Mast/stem cell growth factor receptor Kit

Summary

UniProt ID

P05532

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003283
GlyGen: P05532
PubChem: P05532

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Magnesium
Metal-binding
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 71 in total

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GO Term
hematopoietic stem cell migration
response to cadmium ion
mast cell proliferation
positive regulation of mast cell proliferation
melanocyte adhesion
positive regulation of pyloric antrum smooth muscle contraction
positive regulation of colon smooth muscle contraction
positive regulation of vascular associated smooth muscle cell differentiation
regulation of cell shape
visual learning

Displaying **all 9** entries
GO Term
fibrillar center
external side of plasma membrane
cell surface
extracellular space
plasma membrane
cell-cell junction
receptor complex
acrosomal vesicle
cytoplasmic side of plasma membrane

Displaying **all 10** entries
GO Term
protease binding
transmembrane receptor protein tyrosine kinase activity
ATP binding
growth factor binding
cytokine binding
SH2 domain binding
protein homodimerization activity
protein tyrosine kinase activity
metal ion binding
stem cell factor receptor activity

Annotation information from UniProt.

Sequence

MRGARGAWDLLCVLLVLLRGQTATSQPSASPGEPSPPSIHPAQSELIVEAGDTLSLTCIDPDFVRWTFKTYFNEMVENKKNEWIQEKAEATRTGTYTCSNSNGLTSSIYVFVRDPAKLFLVGLPLFGKEDSDALVRCPLTDPQVSNYSLIECDGKSLPTDLTFVPNPKAGITIKNVKRAYHRLCVRCAAQRDGTWLHSDKFTLKVRAAIKAIPVVSVPETSHLLKKGDTFTVVCTIKDVSTSVNSMWLKMNPQPQHIAQVKHNSWHRGDFNYERQETLTISSARVDDSGVFMCYANNTFGSANVTTTLKVVEKGFINISPVKNTTVFVTDGENVDLVVEYEAYPKPEHQQWIYMNRTSANKGKDYVKSDNKSNIRYVNQLRLTRLKGTEGGTYTFLVSNSDASASVTFNVYVNTKPEILTYDRLINGMLQCVAEGFPEPTIDWYFCTGAEQRCTTPVSPVDVQVQNVSVSPFGKLVVQSSIDSSVFRHNGTVECKASNDVGKSSAFFNFAFKGNNKEQIQAHTLFTPLLIGFVVAAGAMGIIVMVLTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFIFSKQEEQAEAALYKNLLHSTEPSCDSSNEYMDMKPGVSYVVPTKTDKRRSARIDSYIERDVTPAIMEDDELALDLDDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHIYSNLANCNPNPENPVVVDHSVRVNSVGSSASSTQPLLVHEDA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
146	N-linked (GlcNAc...) asparagine		G86182NS	GlycoProtDB UniProt GlyGen
296	N-linked (GlcNAc...) asparagine	17255936		UniProt GlyGen
303	N-linked (GlcNAc...) asparagine	17255936	G37412TK	UniProt GlyGen
323	N-linked (GlcNAc...) asparagine			UniProt GlyGen
355	N-linked (GlcNAc...) asparagine			UniProt GlyGen
370	N-linked (GlcNAc...) asparagine			UniProt GlyGen
466	N-linked (GlcNAc...) asparagine		G43223CG	UniProt GlyGen
489	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
PI3K/AKT Signaling	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
Regulation of KIT signaling	Mus musculus
Signaling by SCF-KIT	Mus musculus
Transcriptional and post-translational regulation of MITF-M expression and activity	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements