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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Calpain-1 catalytic subunit
Summary
- UniProt ID
- P07384
- Gene Symbol
-
- CAPN1
- CANPL1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P07384
- PubChem
- P07384
- The Human Metabolome Database
- HMDBP07544
- RaftProt
- P07384
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Autocatalytic cleavage
- Calcium
- Cell membrane
- Cytoplasm
- Disease variant
- Hereditary spastic paraplegia
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Thiol protease
- Gene Ontology (GO)
| GO Term |
|---|
| cytosol |
| extracellular region |
| cytoplasm |
| mitochondrion |
| lysosome |
| plasma membrane |
| membrane |
| calpain complex |
| ficolin-1-rich granule lumen |
| focal adhesion |
| GO Term |
|---|
| calcium ion binding |
| peptidase activity |
| calcium-dependent cysteine-type endopeptidase activity |
Sequence
MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
Glycosylation Sites
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Degradation of the extracellular matrix | Homo sapiens |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | Homo sapiens |
| Formation of the cornified envelope | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
