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MIRAGE
cAMP-dependent protein kinase type I-alpha regulatory subunit
Summary
- UniProt ID
- P10644
- Gene Symbol
-
- PKR1
- PRKAR1
- PRKAR1A
- TSE1
- Gene ID
- 5573
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cell membrane
- Cushing syndrome
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Phosphoprotein
- Reference proteome
- Repeat
- cAMP-binding
- Gene Ontology (GO)
| GO Term |
|---|
| sperm head-tail coupling apparatus |
| multivesicular body |
| centrosome |
| nucleotide-activated protein kinase complex |
| plasma membrane raft |
| ciliary base |
| cAMP-dependent protein kinase complex |
| glutamatergic synapse |
| cytoplasm |
| membrane |
Sequence
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 124 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ADORA2B mediated anti-inflammatory cytokines production | Homo sapiens |
| ALK mutants bind TKIs | Homo sapiens |
| CREB1 phosphorylation through the activation of Adenylate Cyclase | Homo sapiens |
| DARPP-32 events | Homo sapiens |
| FCGR3A-mediated IL10 synthesis | Homo sapiens |
| Factors involved in megakaryocyte development and platelet production | Homo sapiens |
| GPER1 signaling | Homo sapiens |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | Homo sapiens |
| Hedgehog 'off' state | Homo sapiens |
| High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050471 | Carney complex | |
| DOID:0070546 | primary pigmented nodular adrenocortical disease 1 | |
| DOID:14669 | acrodysostosis |
