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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Chromogranin-A
Summary
- UniProt ID
- P10645
- Gene Symbol
-
- CHGA
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P10645
- PubChem
- P10645
- The Human Metabolome Database
- HMDBP07615
Annotation
- Keyword
-
- 3D-structure
- Amidation
- Antibiotic
- Calcium
- Cleavage on pair of basic residues
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Fungicide
- Oxidation
- Phosphoprotein
- Proteoglycan
- Reference proteome
- Secreted
- Signal
- Sulfation
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of relaxation of cardiac muscle |
| GO Term |
|---|
| extracellular region |
| extracellular space |
| secretory granule |
| chromaffin granule |
| perinuclear region of cytoplasm |
| neuronal dense core vesicle |
| transport vesicle |
Sequence
MRSAAVLALLLCAGQVTALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEMAVVPQGLFRGGKSGELEQEEERLSKEWEDSKRWSKMDQLAKELTAEKRLEGQEEEEDNRDSSMKLSFRARAYGFRGPGPQLRRGWRPSSREDSLEAGLPLQVRGYPEEKKEEEGSANRRPEDQELESLSAIEAELEKVAHQLQALRRG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 48 |
|
|||
| 181 | O-linked (GalNAc...) threonine | |||
| 183 | O-linked (GalNAc...) threonine | |||
| 191 |
|
|||
| 251 | O-linked (GalNAc...) threonine | |||
| 424 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
|
|
G43417UB
G01614ZM
G81006GJ
G65562ZE
G74722FL
G00031MO
G29931IJ
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antimicrobial peptides | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050424 | familial adenomatous polyposis | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050757 | deafness-dystonia-optic neuronopathy syndrome | |
| DOID:0050771 | pheochromocytoma | |
| DOID:0050773 | paraganglioma | |
| DOID:0050865 | tongue squamous cell carcinoma | |
| DOID:0050902 | medulloblastoma | |
| DOID:0060180 | colitis | |
| DOID:0060183 | collagenous colitis | |
| DOID:0060184 | lymphocytic colitis |
