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Repository for lectin-assisted multimodality data
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MIRAGE
Perforin-1
Summary
- UniProt ID
- P10820
- Gene Symbol
-
- Pfp
- Prf1
- Gene ID
- 18646
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Cytolysis
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Endosome
- Glycoprotein
- Lysosome
- Metal-binding
- Reference proteome
- Secreted
- Signal
- Transmembrane beta strand
- Gene Ontology (GO)
| GO Term |
|---|
| cytolytic granule |
| endosome lumen |
| immunological synapse |
| extracellular region |
| plasma membrane |
| membrane |
| cytoplasmic vesicle |
| cytosol |
| GO Term |
|---|
| pore-forming activity |
| wide pore channel activity |
| identical protein binding |
| calcium ion binding |
Sequence
MATCLFLLGLFLLLPRPVPAPCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQATPEQFSTWTASLPSNPGLVDYSLEPLHTLLEEQNPKREALRQAISHYIMSRARWQNCSRPCRSGQHKSSHDSCQCECQDSKVTNQDCCPRQRGLAHLVVSNFRAEHLWGDYTTATDAYLKVFFGGQEFRTGVVWNNNNPRWTDKMDFENVLLSTGGPLRVQVWDADYGWDDDLLGSCDRSPHSGFHEVTCELNHGRVKFSYHAKCLPHLTGGTCLEYAPQGLLGDPPGNRSGAVW
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110922 | familial hemophagocytic lymphohistiocytosis 2 | |
| DOID:2377 | multiple sclerosis | |
| DOID:9744 | type 1 diabetes mellitus |
