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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Platelet glycoprotein Ib beta chain
Summary
- UniProt ID
- P13224
- Gene Symbol
-
- GP1BB
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Bernard Soulier syndrome
- Blood coagulation
- Cell adhesion
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Leucine-rich repeat
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| glycoprotein Ib-IX-V complex |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| identical protein binding |
Sequence
MGSGPRGALSLLLLLLAPPSRPAAGCPAPCSCAGTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNLTALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALRGRLLPYLAEDELRAACAPGPLCWGALAAQLALLGLGLLHALLLVLLLCRLRRLRARARARAAARLSLTDPLVAERAGTDES
Glycosylation Sites
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Defective F9 activation | Homo sapiens |
| Defective binding of VWF variant to GPIb:IX:V | Homo sapiens |
| Enhanced binding of GP1BA variant to VWF multimer:collagen | Homo sapiens |
| GP1b-IX-V activation signalling | Homo sapiens |
| Intrinsic Pathway of Fibrin Clot Formation | Homo sapiens |
| Platelet Adhesion to exposed collagen | Homo sapiens |
| Platelet Aggregation (Plug Formation) | Homo sapiens |
