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Membrane cofactor protein

Summary

UniProt ID

P15529

Gene Symbol

CD46
MCP
MIC10

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011538

GlyConnect

1501

GlyGen

P15529

PubChem

P15529

The O-GlcNAc Database

P15529

RaftProt

P15529

O-GlcNAcAtlas

P15529

Annotation

Keyword

3D-structure
Alternative splicing
Complement pathway
Cytoplasmic vesicle
Direct protein sequencing
Disease variant
Disulfide bond
Fertilization
Glycoprotein
Hemolytic uremic syndrome
Host cell receptor for virus entry
Host-virus interaction
Phosphoprotein
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Gene Ontology (GO)

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GO Term
regulation of Notch signaling pathway
adaptive immune response
T cell mediated immunity
single fertilization
positive regulation of gene expression
negative regulation of gene expression
positive regulation of T cell proliferation
positive regulation of memory T cell differentiation
innate immune response
sequestering of extracellular ligand from receptor

Displaying **all 6** entries
GO Term
cell surface
extracellular space
plasma membrane
focal adhesion
extracellular exosome
inner acrosomal membrane

Displaying **all 3** entries
GO Term
signaling receptor activity
virus receptor activity
cadherin binding

Annotation information from UniProt.

Sequence

MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTDETHREVKFTSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	GlyTouCan ID	Source
83		G89827JR G07810QS G50856PC G82443XX G78649WQ G12341GU G76417NN G15169WU G70232NH G69521XL G03644CB G13131HA G80075MS G57776ZS G28622IK G90382BL G85282JO G04854VP G94470IW G34989PA G43669FQ G45395BF G20706XG G14972EH G43223CG G08918WF G00912UN G92551JA G61256FT G87661QW G83646BJ G04657PL G27058EU G41071NU G08290VR G80920RR G62765YT G31852PQ G23719VF G41247ZX G92275SC	GlycoProtDB UniProt GlyGen GlyConnect
85		G49108TO	GlyGen The O-GlcNAc Database
114			UniProt GlyGen
163	O-linked (GalNAc...) threonine		UniProt GlyGen
273		G70232NH G80075MS G85282JO G94470IW G92135MA G98611JV G34989PA G40834TG G45395BF G59324HL G14972EH G43223CG G60177UT G83229XP G08918WF G00912UN G48414YA G70441OD G87661QW G83646BJ G04657PL G25451PN G27058EU G84452RH G60033FS G41071NU G86182NS G92406TI G80920RR G90659AW G62765YT	GlycoProtDB UniProt GlyGen GlyConnect
290	O-linked (GalNAc...) serine		UniProt GlyGen
291	O-linked (GalNAc...) serine		UniProt GlyGen
292	O-linked (GalNAc...) threonine		UniProt GlyGen
298	O-linked (GalNAc...) serine		UniProt GlyGen
300	O-linked (GalNAc...) serine		UniProt GlyGen