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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD44 antigen
Summary
- UniProt ID
- P16070
- Gene Symbol
-
- CD44
- LHR
- MDU2
- MDU3
- MIC4
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011556
- GlyConnect
- GlyGen
- P16070
- PubChem
- P16070
- The Human Metabolome Database
- HMDBP01716
- The O-GlcNAc Database
- P16070
- RaftProt
- P16070
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell adhesion
- Cell membrane
- Cell projection
- Direct protein sequencing
- Disulfide bond
- Phosphoprotein
- Proteoglycan
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| microvillus |
| secretory granule membrane |
| cell projection |
| extracellular exosome |
| basolateral plasma membrane |
| apical plasma membrane |
| lamellipodium membrane |
| cytosol |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| cytokine receptor activity |
| collagen binding |
| hyaluronic acid binding |
Sequence
MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 25 | N-linked (GlcNAc...) asparagine | |||
| 57 | N-linked (GlcNAc...) asparagine |
|
||
| 100 | N-linked (GlcNAc...) asparagine |
|
||
| 110 | N-linked (GlcNAc...) asparagine |
|
||
| 120 | N-linked (GlcNAc...) asparagine |
|
||
| 162 |
|
|||
| 163 |
|
|||
| 174 |
|
|||
| 180 | O-linked (Xyl...) (chondroitin sulfate) serine |
|
||
| 197 |
|
G48414YA
G53075ES
G94831VI
G39595FH
G81637OR
G62461SM
G82443XX
G55412XP
G05962QB
G64394MX
G13694XX
G76417NN
G23010ZW
G15169WU
G70232NH
G37818NZ
G57888GL
G69521XL
G70888PK
G33791AF
G06247RL
G47518TP
G37881RL
G77582RK
G20312EM
G80075MS
G11629QQ
G57776ZS
G60834IK
G95133RI
G86880BF
G27947YN
G52527GH
G90382BL
G91473PK
G90093AU
G56784JY
G87123QX
G96577RX
G79666IR
G65019XG
G98611JV
G06330RB
G40834TG
G47012YE
G51413EV
G22310AV
G45395BF
G59324HL
G66163OV
G40926MX
G59536GA
G02030ZB
G43223CG
G40574BA
G82830MN
G08918WF
G75983OB
G00912UN
G66760KM
G83646BJ
G80223IX
G25418HZ
G25451PN
G27058EU
G84452RH
G46524LG
G44215PV
G06356OH
G59626AS
G77547TA
G57321FI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| Hyaluronan uptake and degradation | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12895 | keratoconjunctivitis sicca | |
| DOID:12918 | thromboangiitis obliterans | |
| DOID:1294 | vulva carcinoma | |
| DOID:13068 | renal osteodystrophy | |
| DOID:13072 | acquired hyperkeratosis | |
| DOID:1312 | focal segmental glomerulosclerosis | |
| DOID:13139 | crescentic glomerulonephritis | |
| DOID:1319 | brain cancer | |
| DOID:13206 | nodular prostate | |
| DOID:13207 | proliferative diabetic retinopathy |
