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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD44 antigen
Summary
- UniProt ID
- P16070
- Gene Symbol
-
- CD44
- LHR
- MDU2
- MDU3
- MIC4
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011556
- GlyConnect
- GlyGen
- P16070
- PubChem
- P16070
- The Human Metabolome Database
- HMDBP01716
- The O-GlcNAc Database
- P16070
- RaftProt
- P16070
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell adhesion
- Cell membrane
- Cell projection
- Direct protein sequencing
- Disulfide bond
- Phosphoprotein
- Proteoglycan
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| microvillus |
| secretory granule membrane |
| cell projection |
| extracellular exosome |
| basolateral plasma membrane |
| apical plasma membrane |
| lamellipodium membrane |
| cytosol |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| cytokine receptor activity |
| collagen binding |
| hyaluronic acid binding |
Sequence
MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 199 |
|
|||
| 200 |
|
|||
| 271 |
|
|||
| 282 |
|
|
||
| 318 |
|
|||
| 325 |
|
|||
| 330 |
|
|||
| 332 |
|
|||
| 350 | N-linked (GlcNAc...) asparagine |
|
||
| 398 |
|
G53434XO
G57321FI
G43417UB
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| Hyaluronan uptake and degradation | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:4897 | bile duct carcinoma | |
| DOID:4903 | granular cell carcinoma | |
| DOID:4905 | pancreatic carcinoma | |
| DOID:4916 | pituitary carcinoma | |
| DOID:4928 | intrahepatic cholangiocarcinoma | |
| DOID:4929 | tubular adenocarcinoma | |
| DOID:4932 | ampulla of Vater carcinoma | |
| DOID:4947 | cholangiocarcinoma | |
| DOID:4948 | gallbladder carcinoma | |
| DOID:4959 | epidermolysis bullosa dystrophica |
