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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
CD44 antigen
Summary
- UniProt ID
- P16070
- Gene Symbol
-
- CD44
- LHR
- MDU2
- MDU3
- MIC4
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011556
- GlyConnect
- GlyGen
- P16070
- PubChem
- P16070
- The Human Metabolome Database
- HMDBP01716
- The O-GlcNAc Database
- P16070
- RaftProt
- P16070
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood group antigen
- Cell adhesion
- Cell membrane
- Cell projection
- Direct protein sequencing
- Disulfide bond
- Phosphoprotein
- Proteoglycan
- Receptor
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi apparatus |
| plasma membrane |
| microvillus |
| secretory granule membrane |
| cell projection |
| extracellular exosome |
| basolateral plasma membrane |
| apical plasma membrane |
| lamellipodium membrane |
| cytosol |
| GO Term |
|---|
| transmembrane signaling receptor activity |
| cytokine receptor activity |
| collagen binding |
| hyaluronic acid binding |
Sequence
MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 529 |
|
|||
| 541 |
|
|||
| 545 |
|
|||
| 546 |
|
|||
| 548 | N-linked (GlcNAc...) asparagine | |||
| 550 |
|
|||
| 553 |
|
|||
| 554 |
|
|||
| 555 |
|
|||
| 560 |
|
|
G57321FI
G10486CT
G53434XO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| Hyaluronan uptake and degradation | Homo sapiens |
| Integrin cell surface interactions | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060874 | isolated growth hormone deficiency type IB | |
| DOID:0060875 | isolated growth hormone deficiency type III | |
| DOID:0060891 | Parkinson's disease 19A | |
| DOID:0060895 | Parkinson's disease 4 | |
| DOID:0060896 | Parkinson's disease 23 | |
| DOID:0070161 | hereditary sensory and autonomic neuropathy type 2 | |
| DOID:0070324 | systemic Epstein-Barr virus positive T-cell lymphoma of childhood | |
| DOID:0070329 | mitochondrial DNA depletion syndrome | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080147 | lymphoblastic lymphoma |
