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Lysosomal acid glucosylceramidase

Summary

UniProt ID

P17439

Gene Symbol

Gba
Gba1

Gene ID

14466

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003442

GlyConnect

Glucosylceramidase

GlyGen

P17439

PubChem

P17439

SwissLipids

SLP:000001930

RaftProt

P17439

Re-Glyco

P17439

Annotation

Keyword

Cholesterol metabolism
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosidase
Glycosyltransferase
Lysosome
Membrane
Reference proteome
Signal
Sphingolipid metabolism

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
extracellular space
lysosome
endoplasmic reticulum
Golgi apparatus
trans-Golgi network
lysosomal membrane
lysosomal lumen

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 55 in total

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GO Term
mitochondrion organization
central nervous system development
antigen processing and presentation
regulation of membrane potential
cell maturation
homeostasis of number of cells
nervous system process
neuromuscular process
regulation of protein metabolic process
negative regulation of protein metabolic process

Displaying **all 8** entries
GO Term
hydrolase activity
signaling receptor binding
glucosyltransferase activity
scavenger receptor binding
galactosylceramidase activity
glucosylceramidase activity
beta-glucosidase activity
steryl-beta-glucosidase activity

Annotation information from UniProt.

Sequence

MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine			UniProt GlyGen
78	N-linked (GlcNAc...) asparagine		G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
165	N-linked (GlcNAc...) (high mannose) asparagine	16170054	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
289	N-linked (GlcNAc...) asparagine	19349973	G83460ZZ G39188ZX G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
480	N-linked (GlcNAc...) asparagine			UniProt GlyGen