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Lysosomal acid glucosylceramidase

Summary

UniProt ID

P17439

Gene Symbol

Gba1
Gba

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003442

GlyConnect

2339

GlyGen

P17439

PubChem

P17439

SwissLipids

SLP:000001930

RaftProt

P17439

Annotation

Keyword

Cholesterol metabolism
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosidase
Glycosyltransferase
Lysosome
Membrane
Reference proteome
Signal
Sphingolipid metabolism

Gene Ontology (GO)

Displaying entries **51 - 56** of 56 in total

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GO Term
positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
autophagosome organization
positive regulation of protein dephosphorylation
positive regulation of protein-containing complex disassembly
sphingosine biosynthetic process
positive regulation of neuronal action potential

Displaying **all 7** entries
GO Term
endoplasmic reticulum
Golgi apparatus
trans-Golgi network
extracellular space
lysosome
lysosomal membrane
lysosomal lumen

Displaying **all 8** entries
GO Term
signaling receptor binding
glucosyltransferase activity
hydrolase activity
scavenger receptor binding
galactosylceramidase activity
glucosylceramidase activity
beta-glucosidase activity
steryl-beta-glucosidase activity

Annotation information from UniProt.

Sequence

MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine			UniProt GlyGen
78	N-linked (GlcNAc...) asparagine		G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
165	N-linked (GlcNAc...) (high mannose) asparagine	16170054	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
289	N-linked (GlcNAc...) asparagine	19349973	G83460ZZ G39188ZX G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
480	N-linked (GlcNAc...) asparagine			UniProt GlyGen