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Lysosomal acid glucosylceramidase

Summary

UniProt ID

P17439

Gene Symbol

Gba1
Gba

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003442

GlyConnect

2339

GlyGen

P17439

PubChem

P17439

SwissLipids

SLP:000001930

RaftProt

P17439

Annotation

Keyword

Cholesterol metabolism
Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosidase
Glycosyltransferase
Lysosome
Membrane
Reference proteome
Signal
Sphingolipid metabolism

Gene Ontology (GO)

Displaying entries **11 - 20** of 56 in total

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GO Term
negative regulation of protein metabolic process
glucosylceramide metabolic process
termination of signal transduction
skin epidermis development
positive regulation of proteolysis involved in protein catabolic process
positive regulation of protein lipidation
mitophagy
glucosylceramide catabolic process
autophagy
lysosome organization

Displaying **all 7** entries
GO Term
endoplasmic reticulum
Golgi apparatus
trans-Golgi network
extracellular space
lysosome
lysosomal membrane
lysosomal lumen

Displaying **all 8** entries
GO Term
signaling receptor binding
glucosyltransferase activity
hydrolase activity
scavenger receptor binding
galactosylceramidase activity
glucosylceramidase activity
beta-glucosidase activity
steryl-beta-glucosidase activity

Annotation information from UniProt.

Sequence

MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
38	N-linked (GlcNAc...) asparagine			UniProt GlyGen
78	N-linked (GlcNAc...) asparagine		G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
165	N-linked (GlcNAc...) (high mannose) asparagine	16170054	G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
289	N-linked (GlcNAc...) asparagine	19349973	G83460ZZ G39188ZX G06110VR G74724QE	GlycoProtDB UniProt GlyGen GlyConnect
480	N-linked (GlcNAc...) asparagine			UniProt GlyGen