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MIRAGE
Insulin-like growth factor-binding protein 3

Summary
UniProt ID
P17936
Gene Symbol
  • IBP3
  • IGFBP3
Gene ID
3486
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011577
GlyConnect
GlyGen
P17936
PubChem
P17936
Re-Glyco
P17936
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Apoptosis
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Growth factor binding
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 6 entries
GO Term
endoplasmic reticulum lumen
insulin-like growth factor ternary complex
insulin-like growth factor binding protein complex
extracellular region
extracellular space
nucleus
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 17 in total
Position Description PubMed ID GlyTouCan ID Source
116 N-linked (GlcNAc...) (complex) asparagine
136 N-linked (GlcNAc...) (complex) asparagine
145
148
151
153
155
156
157
161
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Post-translational protein phosphorylation Homo sapiens
Regulation of IGF Activity by IGFBP Homo sapiens
TP53 Regulates Transcription of Death Receptors and Ligands Homo sapiens
Disease
Displaying all 8 entries
DO ID Disease Name Source
DOID:0050589 inflammatory bowel disease
DOID:10283 prostate cancer
DOID:10652 Alzheimer's disease
DOID:1612 breast cancer
DOID:2671 transitional cell carcinoma
DOID:3491 Turner syndrome
DOID:9352 type 2 diabetes mellitus
DOID:9744 type 1 diabetes mellitus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025