GlyCosmos Portal

Submissions

Brain-derived neurotrophic factor

Summary

UniProt ID

P23560

Gene Symbol

BDNF

Organism

Homo sapiens (human)

External Links

GlyGen: P23560
PubChem: P23560

Annotation

Keyword

3D-structure
Alternative promoter usage
Alternative splicing
Cleavage on pair of basic residues
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **11 - 20** of 20 in total

« First

‹ Prev

1

2
GO Term
negative regulation of neuron apoptotic process
neuron projection morphogenesis
positive regulation of synapse assembly
negative regulation of apoptotic signaling pathway
synapse assembly
negative regulation of myotube differentiation
brain-derived neurotrophic factor receptor signaling pathway
nerve growth factor signaling pathway
collateral sprouting
regulation of protein localization to cell surface

Displaying **all 8** entries
GO Term
synaptic vesicle
endoplasmic reticulum lumen
perinuclear region of cytoplasm
extracellular region
extracellular space
cytoplasm
axon
dendrite

Displaying **all 2** entries
GO Term
nerve growth factor receptor binding
growth factor activity

Annotation information from UniProt.

Sequence

MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
121	N-linked (GlcNAc...) asparagine	11152678 19467646	G62765YT	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 13 in total

1

2

Next ›

Last »
Pathway Name	Organism
Activated NTRK2 signals through CDK5	Homo sapiens
Activated NTRK2 signals through FRS2 and FRS3	Homo sapiens
Activated NTRK2 signals through FYN	Homo sapiens
Activated NTRK2 signals through PI3K	Homo sapiens
Activated NTRK2 signals through PLCG1	Homo sapiens
Activated NTRK2 signals through RAS	Homo sapiens
BDNF activates NTRK2 (TRKB) signaling	Homo sapiens
Constitutive Signaling by Aberrant PI3K in Cancer	Homo sapiens
MECP2 regulates transcription of neuronal ligands	Homo sapiens
NPAS4 regulates expression of target genes	Homo sapiens