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Nuclear factor NF-kappa-B p105 subunit

Summary

UniProt ID

P25799

Gene Symbol

Nfkb1

Gene ID

18033

Organism

Mus musculus (house mouse)

External Links

GlyGen: P25799
PubChem: P25799
The O-GlcNAc Database: P25799
O-GlcNAcAtlas: P25799
Re-Glyco: P25799

Annotation

Keyword

3D-structure
ANK repeat
Acetylation
Activator
Alternative splicing
Apoptosis
Cytoplasm
DNA-binding
Direct protein sequencing
Hydroxylation
Isopeptide bond
Lipoprotein
Nucleus
Phosphoprotein
Reference proteome
Repeat
S-nitrosylation
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
chromatin
nucleus
cytoplasm
mitochondrion
NF-kappaB p50/p65 complex
nucleoplasm
cytosol
transcription regulator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

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GO Term
gene expression
negative regulation of cytokine production
apoptotic process
response to muscle stretch
non-canonical NF-kappaB signal transduction
lymph node development
cellular response to nicotine
cellular response to interleukin-6
cellular response to angiotensin
positive regulation of miRNA metabolic process

Displaying entries **1 - 10** of 12 in total

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GO Term
chromatin binding
RNA polymerase II transcription regulatory region sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
transcription coregulator activity
identical protein binding
sequence-specific DNA binding
transcription cis-regulatory region binding

Annotation information from UniProt.

Sequence

MADDDPYGTGQMFHLNTALTHSIFNAELYSPEIPLSTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLTDREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGSTGSPGPGYGYSNYGFPPYGGITFHPGVTKSNAGVTHGTINTKFKNGPKDCAKSDDEESLTLPEKETEGEGPSLPMACTKTEPIALASTMEDKEQDMGFQDNLFLEKALQLARRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRVGADLSLLDRWGNSVLHLAAKEGHDRILSILLKSRKAAPLIDHPNGEGLNAIHIAVMSNSLPCLLLLVAAGAEVNAQEQKSGRTALHLAVEYDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTPLDMAANWQVFDILNGKPYEPVFTSDDILPQGDMKQLTEDTRLQLCKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELMEALQQMGYTEAIEVIQAAFRTPATTASSPVTTAQVHCLPLSSSSTRQHIDELRDSDSVCDSGVETSFRKLSFTESLTGDSPLLSLNKMPHGYGQEGPIEGKI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
890	G49108TO	The O-GlcNAc Database
893	G49108TO	GlyGen
894	G49108TO	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 17** of 17 in total

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Pathway Name	Organism
Neutrophil degranulation	Mus musculus
PKMTs methylate histone lysines	Mus musculus
RIP-mediated NFkB activation via ZBP1	Mus musculus
Regulated proteolysis of p75NTR	Mus musculus
TAK1-dependent IKK and NF-kappa-B activation	Mus musculus
TRAF6 mediated NF-kB activation	Mus musculus
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

International Collaboration

Acknowledgements