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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tyrosine-protein kinase Lyn
Summary
- UniProt ID
- P25911
- Gene Symbol
-
- Lyn
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Cytoplasm
- Golgi apparatus
- Inflammatory response
- Innate immunity
- Myristate
- Nucleus
- Palmitate
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| regulation of platelet aggregation |
| regulation of ERK1 and ERK2 cascade |
| negative regulation of ERK1 and ERK2 cascade |
| cellular response to retinoic acid |
| GO Term |
|---|
| glutamatergic synapse |
| mitochondrial crista |
| cytosol |
| mitochondrial membrane |
| membrane raft |
| adherens junction |
| cell surface |
| extrinsic component of cytoplasmic side of plasma membrane |
| integrin alpha2-beta1 complex |
| nucleus |
Sequence
MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKDPEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 19 |
|
|||
| 267 |
|
G49108TO
G29068FM
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Erythropoietin activates Phosphoinositide-3-kinase (PI3K) | Mus musculus |
| Erythropoietin activates RAS | Mus musculus |
| FCERI mediated Ca+2 mobilization | Mus musculus |
| FCERI mediated MAPK activation | Mus musculus |
| FCERI mediated NF-kB activation | Mus musculus |
| FCGR activation | Mus musculus |
| Fc epsilon receptor (FCERI) signaling | Mus musculus |
| GPVI-mediated activation cascade | Mus musculus |
| Growth hormone receptor signaling | Mus musculus |
| Inactivation of CSF3 (G-CSF) signaling | Mus musculus |
